EMDB/PDB/SASBDBから引用されている文献のデータベース

キーワード
構造解析手法	All X線回折 NMR 電子顕微鏡小角散乱中性子線回折線維回折粉末回折赤外分光 EPR FRET 理論モデルハイブリッド
著者・登録者
ジャーナル
IF	>30 >20 >10 >5 all

タイトル	Crystallographic Fragment Screening of a Bifunctional Proline Catabolic Enzyme Reveals New Inhibitor Templates for Proline Dehydrogenase and L-Glutamate-gamma-semialdehyde Dehydrogenase.
ジャーナル・号・ページ	Molecules, Vol. 29, Year 2024
掲載日	2024年9月10日 (構造データの登録日)
著者	Meeks, K.R. / Bogner, A.N. / Nix, J.C. / Tanner, J.J.
リンク	Molecules / PubMed:39598797
手法	X線回折
解像度	1.32 - 1.8 Å
構造データ	PDB-9dl2: Structure of proline utilization A complexed with 2,3-dihydro-1,4-benzodioxine-5-carboxylic acid 手法: X-RAY DIFFRACTION / 解像度: 1.55 Å PDB-9dl3: Structure of proline utilization A complexed with quinoline-2-carboxylic acid 手法: X-RAY DIFFRACTION / 解像度: 1.77 Å PDB-9dl4: Structure of proline utilization A complexed with 2-pyridinethiol 手法: X-RAY DIFFRACTION / 解像度: 1.8 Å PDB-9dl5: Structure of proline utilization A complexed with 5-chloro-1-indanone 手法: X-RAY DIFFRACTION / 解像度: 1.77 Å PDB-9dl6: Structure of proline utilization A complexed with piperidine-3-carboxylic acid 手法: X-RAY DIFFRACTION / 解像度: 1.42 Å PDB-9dl7: Structure of proline utilization A complexed with 1-(4-fluorophenyl)thiourea 手法: X-RAY DIFFRACTION / 解像度: 1.72 Å PDB-9dl8: Structure of proline utilization A soaked with 4-methoxybenzyl alcohol 手法: X-RAY DIFFRACTION / 解像度: 1.64 Å PDB-9dl9: Structure of proline utilization A co-crystallized with 4-methoxybenzyl alcohol 手法: X-RAY DIFFRACTION / 解像度: 1.32 Å PDB-9e0a: Structure of proline utilization A complexed with 1,4-benzenedimethanol 手法: X-RAY DIFFRACTION / 解像度: 1.39 Å PDB-9e0b: Structure of proline utilization A complexed with (2,3-dihydro-1-benzofuran-5-yl)methanol 手法: X-RAY DIFFRACTION / 解像度: 1.47 Å PDB-9e0c: Structure of proline utilization A complexed with 1-benzofuran-5-ylmethanol 手法: X-RAY DIFFRACTION / 解像度: 1.32 Å PDB-9e0d: Structure of proline utilization A complexed with piperonyl alcohol 手法: X-RAY DIFFRACTION / 解像度: 1.33 Å PDB-9e0e: Structure of proline utilization A complexed with (1H-indol-5-yl)methanol 手法: X-RAY DIFFRACTION / 解像度: 1.37 Å
化合物	ChemComp-FAD: FLAVIN-ADENINE DINUCLEOTIDE / FAD / FADYM ChemComp-PEG: DI(HYDROXYETHYL)ETHER / ジエチレングリコ-ル ChemComp-53E: 2,3-dihydro-1,4-benzodioxine-5-carboxylic acid / 2,3-ジヒドロ-1,4-ベンゾジオキシン-5-カルボン酸 ChemComp-FMT: FORMIC ACID / ギ酸 ChemComp-NAD: NICOTINAMIDE-ADENINE-DINUCLEOTIDE / NADYM ChemComp-SO4: SULFATE ION / 硫酸ジアニオン ChemComp-MG: Unknown entry / マグネシウムジカチオン ChemComp-PGE: TRIETHYLENE GLYCOL / トリエチレングリコ-ル ChemComp-PG4: TETRAETHYLENE GLYCOL / テトラエチレングリコ-ル / 沈殿剤YM ChemComp-HOH: WATER ChemComp-QNC: quinoline-2-carboxylic acid / キナルジン酸 ChemComp-PYS: 2-PYRIDINETHIOL / 2-ピリジンチオ-ル PDB-1bda: CATALYTIC DOMAIN OF HUMAN SINGLE CHAIN TISSUE PLASMINOGEN ACTIVATOR IN COMPLEX WITH DANSYL-EGR-CMK (DANSYL-GLU-GLY-ARG CHLOROMETHYL KETONE) PDB-1bdb: CIS-BIPHENYL-2,3-DIHYDRODIOL-2,3-DEHYDROGENASE FROM PSEUDOMONAS SP. LB400 ChemComp-ID7: (3R)-piperidine-3-carboxylic acid / (R)-ニペコチン酸 ChemComp-8P4: 1-(4-fluorophenyl)thiourea / N¹-(4-フルオロフェニル)チオ尿素 PDB-1bdd: STAPHYLOCOCCUS AUREUS PROTEIN A, IMMUNOGLOBULIN-BINDING B DOMAIN, NMR, MINIMIZED AVERAGE STRUCTURE ChemComp-1PE: PENTAETHYLENE GLYCOL / ペンタエチレングリコ-ル / 沈殿剤YM PDB-1bdw: GRAMICIDIN D FROM BACILLUS BREVIS (ACTIVE FORM) PDB-1aqc: X11 PTB DOMAIN-10MER PEPTIDE COMPLEX PDB-1bdx: E. COLI DNA HELICASE RUVA WITH BOUND DNA HOLLIDAY JUNCTION, ALPHA CARBONS AND PHOSPHATE ATOMS ONLY PDB-1bdv: ARC FV10 COCRYSTAL PDB-1bdu: E. COLI THYMIDYLATE SYNTHASE COMPLEXED WITH DURD
由来	sinorhizobium meliloti (根粒菌)
キーワード	OXIDOREDUCTASE / FLAVOENZYME / ROSSMANN FOLD / PROLINE DEHYDROGENASE / ALDEHYDE DEHYDROGENASE / PROLINE CATABOLISM / SUBSTRATE CHANNELING / BIFUNCTIONAL ENZYME