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TitleDiscovery of CHD1 Antagonists for PTEN-Deficient Prostate Cancer.
Journal, issue, pagesJ. Med. Chem., Vol. 67, Page 20056-20075, Year 2024
Publish dateOct 17, 2023 (structure data deposition date)
AuthorsJohnson, R.L. / Graboski, A.L. / Li, F. / Norris-Drouin, J.L. / Walton, W.G. / Arrowsmith, C.H. / Redinbo, M.R. / Frye, S.V. / James, L.I.
External linksJ. Med. Chem. / PubMed:39508435
MethodsX-ray diffraction
Resolution3.1 Å
Structure data

PDB-8umg:
Chromodomains of human CHD1 complexed with UNC10142
Method: X-RAY DIFFRACTION / Resolution: 3.1 Å

Chemicals


ChemComp, No image

ChemComp-X31:
Unknown entry

ChemComp-CL:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsPEPTIDE BINDING PROTEIN / CHD1 / Chromodomain-Helicase DNA-binding 1 / Methyllysine Reader

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