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TitleStructural insight into rabies virus neutralization revealed by an engineered antibody scaffold.
Journal, issue, pagesStructure, Vol. 32, Page 2220-, Year 2024
Publish dateNov 10, 2023 (structure data deposition date)
AuthorsKedari, A. / Iheozor-Ejiofor, R. / Salminen, P. / Ugurlu, H. / Makela, A.R. / Levanov, L. / Vapalahti, O. / Hytonen, V.P. / Saksela, K. / Rissanen, I.
External linksStructure / PubMed:39471803
MethodsX-ray diffraction
Resolution2.38 - 2.7 Å
Structure data

PDB-8r3w:
Crystal structure of a homospecific CR57 diabody
Method: X-RAY DIFFRACTION / Resolution: 2.38 Å

PDB-8r40:
Crystal structure of diabody CR57 in complex with rabies virus protein G domain III
Method: X-RAY DIFFRACTION / Resolution: 2.7 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-GOL:
GLYCEROL

Source
  • homo sapiens (human)
  • rabies virus cvs-11
KeywordsIMMUNE SYSTEM / human monoclonal antibody CR57 / diabody / monospecific diabody / rabies antibody / VIRAL PROTEIN / Rabies glycoprotein / antibody-antigen complex / CR57 diabody / antibody / engineered antibody

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