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TitleActivation of parkin by a molecular glue.
Journal, issue, pagesNat Commun, Vol. 15, Page 7707-7707, Year 2024
Publish dateFeb 21, 2024 (structure data deposition date)
AuthorsSauve, V. / Stefan, E. / Croteau, N. / Goiran, T. / Fakih, R. / Bansal, N. / Hadzipasic, A. / Fang, J. / Murugan, P. / Chen, S. ...Sauve, V. / Stefan, E. / Croteau, N. / Goiran, T. / Fakih, R. / Bansal, N. / Hadzipasic, A. / Fang, J. / Murugan, P. / Chen, S. / Fon, E.A. / Hirst, W.D. / Silvian, L.F. / Trempe, J.F. / Gehring, K.
External linksNat Commun / PubMed:39300082
MethodsX-ray diffraction
Resolution2.5 Å
Structure data

PDB-8w31:
Crystal structure of parkin (R0RB):2pUb with activator compound
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

Chemicals

ChemComp-ZN:
Unknown entry

PDB-1ae9:
STRUCTURE OF THE LAMBDA INTEGRASE CATALYTIC CORE

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • rattus norvegicus (Norway rat)
  • homo sapiens (human)
KeywordsLIGASE / E3-ubiquitin ligase / activator

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