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TitleA broadly protective antibody targeting glycoprotein Gn inhibits severe fever with thrombocytopenia syndrome virus infection.
Journal, issue, pagesNat Commun, Vol. 15, Page 7009-7009, Year 2024
Publish dateDec 22, 2023 (structure data deposition date)
AuthorsRen, X. / Sun, J. / Kuang, W. / Yu, F. / Wang, B. / Wang, Y. / Deng, W. / Xu, Z. / Yang, S. / Wang, H. ...Ren, X. / Sun, J. / Kuang, W. / Yu, F. / Wang, B. / Wang, Y. / Deng, W. / Xu, Z. / Yang, S. / Wang, H. / Hu, Y. / Deng, Z. / Ning, Y.J. / Zhao, H.
External linksNat Commun / PubMed:39147753
MethodsX-ray diffraction
Resolution2.45 - 3.53 Å
Structure data

PDB-8xk5:
SNB1G11 Fab bound to SFTSV glycoprotein Gn
Method: X-RAY DIFFRACTION / Resolution: 3.05 Å

PDB-8xk6:
S2A5 Fab bound to SFTSV glycoprotein Gn
Method: X-RAY DIFFRACTION / Resolution: 2.45 Å

PDB-8xk8:
N1D10 Fab bound to SFTSV glycoprotein-Gn
Method: X-RAY DIFFRACTION / Resolution: 3.53 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
  • severe fever with thrombocytopenia syndrome virus
KeywordsVIRAL PROTEIN / glycoprotein / Gn / Fab

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