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Structure paper

TitleCLASP-mediated competitive binding in protein condensates directs microtubule growth.
Journal, issue, pagesNat Commun, Vol. 15, Page 6509-6509, Year 2024
Publish dateSep 23, 2023 (structure data deposition date)
AuthorsJia, X. / Lin, L. / Guo, S. / Zhou, L. / Jin, G. / Dong, J. / Xiao, J. / Xie, X. / Li, Y. / He, S. ...Jia, X. / Lin, L. / Guo, S. / Zhou, L. / Jin, G. / Dong, J. / Xiao, J. / Xie, X. / Li, Y. / He, S. / Wei, Z. / Yu, C.
External linksNat Commun / PubMed:39095354
MethodsX-ray diffraction
Resolution1.4 - 3.801 Å
Structure data

PDB-8whh:
Crystal structure of Se-Met derivative CLASP2 in complex with CLIP170
Method: X-RAY DIFFRACTION / Resolution: 3.801 Å

PDB-8whi:
Crystal structure of native CLASP2 in complex with CLIP170
Method: X-RAY DIFFRACTION / Resolution: 1.853 Å

PDB-8whj:
Crystal structure of CLASP2 TOG4 fused with LL5beta
Method: X-RAY DIFFRACTION / Resolution: 1.4 Å

PDB-8whk:
Crystal structure of CLASP2 in complex with LL5beta
Method: X-RAY DIFFRACTION / Resolution: 2.401 Å

PDB-8whl:
Crystal structure of CLASP2 in complex with CENP-E
Method: X-RAY DIFFRACTION / Resolution: 3.2 Å

PDB-8whm:
Crystal structure of the ELKS2/LL5beta complex
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

Chemicals

ChemComp-PEG:
DI(HYDROXYETHYL)ETHER

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-HOH:
WATER

ChemComp-CL:
Unknown entry

ChemComp-ACT:
ACETATE ION

ChemComp-MLA:
MALONIC ACID

Source
  • homo sapiens (human)
  • rattus norvegicus (Norway rat)
KeywordsPROTEIN BINDING / Complex

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