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Structure paper

TitleStructural insights into rapamycin-induced oligomerization of a FRB-FKBP fusion protein.
Journal, issue, pagesFebs Lett., Vol. 598, Page 2292-2305, Year 2024
Publish dateDec 19, 2023 (structure data deposition date)
AuthorsInobe, T. / Sakaguchi, R. / Obita, T. / Mukaiyama, A. / Koike, S. / Yokoyama, T. / Mizuguchi, M. / Akiyama, S.
External linksFebs Lett. / PubMed:39031920
MethodsX-ray diffraction
Resolution1.85 Å
Structure data

PDB-8xi9:
Crystal structure of FRB-FKBP fusion protein in complex with rapamycin
Method: X-RAY DIFFRACTION / Resolution: 1.85 Å

Chemicals

ChemComp-RAP:
RAPAMYCIN IMMUNOSUPPRESSANT DRUG / immunosuppressant, antibiotic*YM

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsSIGNALING PROTEIN / Rapamycin

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