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Structure paper

TitleEnhanced binding of guanylated poly(A) RNA by the LaM domain of LARP1.
Journal, issue, pagesRna Biol., Vol. 21, Page 7-16, Year 2024
Publish dateNov 1, 2021 (structure data deposition date)
AuthorsKozlov, G. / Jiang, J. / Rutherford, T. / Noronha, A.M. / Wilds, C.J. / Gehring, K.
External linksRna Biol. / PubMed:39016322
MethodsX-ray diffraction
Resolution1.2 - 1.63 Å
Structure data

PDB-7sow:
LaM domain of human LARP1 in complex with UUUUUU
Method: X-RAY DIFFRACTION / Resolution: 1.3 Å

PDB-8ey6:
LaM domain of human LARP1 in complex with AAAAAG RNA
Method: X-RAY DIFFRACTION / Resolution: 1.63 Å

PDB-8ey7:
LaM domain of human LARP1 in complex with AAAGAA RNA
Method: X-RAY DIFFRACTION / Resolution: 1.35 Å

PDB-8ey8:
LaM domain of human LARP1 in complex with AAAAGA RNA
Method: X-RAY DIFFRACTION / Resolution: 1.3 Å

PDB-8g90:
LaM domain of human LARP1 in complex with Sp phosphorothioate isomer of AAAAA(SRA) RNA
Method: X-RAY DIFFRACTION / Resolution: 1.2 Å

PDB-8g91:
LaM domain of human LARP1 in complex with Rp phosphorothioate isomer of AAAAA(SRA) RNA
Method: X-RAY DIFFRACTION / Resolution: 1.2 Å

Chemicals

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-HOH:
WATER

ChemComp-SO4:
SULFATE ION

ChemComp-GOL:
GLYCEROL

Source
  • homo sapiens (human)
  • synthetic construct (others)
KeywordsRNA BINDING PROTEIN/RNA / Winged helix fold / RNA binding domain / RNA BINDING PROTEIN / RNA BINDING PROTEIN-RNA complex

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