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TitleCrystal structure of the class A extended-spectrum beta-lactamase CTX-M-96 in complex with relebactam at 1.03 Angstrom resolution.
Journal, issue, pagesAntimicrob. Agents Chemother., Vol. 68, Page e0172123-e0172123, Year 2024
Publish dateSep 14, 2022 (structure data deposition date)
AuthorsGhiglione, B. / Rodriguez, M.M. / Penzotti, P. / Bethel, C.R. / Gutkind, G. / Bonomo, R.A. / Klinke, S. / Power, P.
External linksAntimicrob. Agents Chemother. / PubMed:38990013
MethodsX-ray diffraction
Resolution1.03 Å
Structure data

PDB-8ehh:
Crystal structure of the class A extended-spectrum beta-lactamase CTX-M-96 in complex with relebactam at 1.03 Angstrom resolution
Method: X-RAY DIFFRACTION / Resolution: 1.03 Å

Chemicals

ChemComp-MK7:
(2S,5R)-1-formyl-N-(piperidin-4-yl)-5-[(sulfooxy)amino]piperidine-2-carboxamide

ChemComp-HOH:
WATER

Source
  • klebsiella pneumoniae (bacteria)
KeywordsANTIMICROBIAL PROTEIN / beta-lactamase inhibitor / DBO / ESBL / ceftazidimase

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