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Structure paper

TitleStructural and functional characterization of cyclic pyrimidine-regulated anti-phage system.
Journal, issue, pagesNat Commun, Vol. 15, Page 5634-5634, Year 2024
Publish dateJun 20, 2023 (structure data deposition date)
AuthorsHou, M.H. / Chen, C.J. / Yang, C.S. / Wang, Y.C. / Chen, Y.
External linksNat Commun / PubMed:38965224
MethodsX-ray diffraction
Resolution1.83 - 2.858 Å
Structure data

PDB-8jsf:
Crystal structure of a cytidylate cyclase from multidrug-resistant bacterium Elizabethkingia anopheles
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

PDB-8jsj:
Crystal structure of an N-terminal cyclic nucleotide-binding domain of a PycTIR from Novosphingobium pentaromativorans
Method: X-RAY DIFFRACTION / Resolution: 2.858 Å

PDB-8jsk:
Crystal structure of an N-terminal cyclic nucleotide-binding domain of a PycTIR from Pseudovibrio sp. in complex with cUMP
Method: X-RAY DIFFRACTION / Resolution: 2.401 Å

PDB-8jsz:
Crystal structure of a uridylate cyclase from Anabaena sp.
Method: X-RAY DIFFRACTION / Resolution: 1.83 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-6SY:
Uridine-3',5'-cyclic monophosphate

ChemComp-ZN:
Unknown entry

ChemComp-CL:
Unknown entry

ChemComp-ACT:
ACETATE ION

ChemComp-GOL:
GLYCEROL

Source
  • elizabethkingia anophelis (bacteria)
  • novosphingobium pentaromativorans us6-1 (bacteria)
  • pseudovibrio sp. w64 (bacteria)
  • anabaena sp. ca (bacteria)
KeywordsTRANSFERASE / Adenylate/guanylate cyclase / SIGNALING PROTEIN / cUMP receptor / Pycsar effector protein

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