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Structure paper

TitleSite-directed mutagenesis reveals the interplay between stability, structure, and enzymatic activity in RidA from Capra hircus.
Journal, issue, pagesProtein Sci., Vol. 33, Page e5036-e5036, Year 2024
Publish dateAug 4, 2023 (structure data deposition date)
AuthorsRizzi, G. / Digiovanni, S. / Degani, G. / Barbiroli, A. / Di Pisa, F. / Popolo, L. / Visentin, C. / Vanoni, M.A. / Ricagno, S.
External linksProtein Sci. / PubMed:38801230
MethodsX-ray diffraction
Resolution1.2 - 2.01 Å
Structure data

PDB-8q3h:
Capra hircus reactive intermediate deaminase A mutant - A108D
Method: X-RAY DIFFRACTION / Resolution: 1.57 Å

PDB-8qok:
Capra hircus reactive intermediate deaminase A mutant - E124A
Method: X-RAY DIFFRACTION / Resolution: 1.2 Å

PDB-8qom:
Capra hircus reactive intermediate deaminase A mutant - R107W
Method: X-RAY DIFFRACTION / Resolution: 1.654 Å

PDB-8qop:
Capra hircus reactive intermediate deaminase A - K78A
Method: X-RAY DIFFRACTION / Resolution: 1.4 Å

PDB-8qoq:
Capra hircus reactive intermediate deaminase A mutant - R107A
Method: X-RAY DIFFRACTION / Resolution: 1.214 Å

PDB-8qos:
Capra hircus reactive intermediate deaminase A - V25W
Method: X-RAY DIFFRACTION / Resolution: 2.01 Å

PDB-8qou:
Reactive intermediate deaminase A mutant - R107K
Method: X-RAY DIFFRACTION / Resolution: 1.4 Å

PDB-8qov:
Capra hircus reactive intermediate deaminase A mutant - I126Y
Method: X-RAY DIFFRACTION / Resolution: 1.6 Å

Chemicals

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

ChemComp-NA:
Unknown entry

ChemComp-K:
Unknown entry

ChemComp-PEG:
DI(HYDROXYETHYL)ETHER

ChemComp-NI:
NICKEL (II) ION

Source
  • capra hircus (goat)
KeywordsUNKNOWN FUNCTION / 2-iminobutanoate/2-iminopropanoate deaminase - Capra hircus / Enzyme / deaminase

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