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-Structure paper
Title | Antisense RNA C9orf72 hexanucleotide repeat associated with amyotrophic lateral sclerosis and frontotemporal dementia forms a triplex-like structure and binds small synthetic ligand. |
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Journal, issue, pages | Nucleic Acids Res., Vol. 52, Page 6707-6717, Year 2024 |
Publish date | Sep 22, 2023 (structure data deposition date) |
Authors | Blaszczyk, L. / Ryczek, M. / Das, B. / Mateja-Pluta, M. / Bejger, M. / Sliwiak, J. / Nakatani, K. / Kiliszek, A. |
External links | Nucleic Acids Res. / PubMed:38738637 |
Methods | X-ray diffraction |
Resolution | 0.918 - 1.5 Å |
Structure data | PDB-8qmh: PDB-8qmi: PDB-9en6: |
Chemicals |
ChemComp-W53: ChemComp-CL: ChemComp-HOH: ChemComp-MG: |
Source |
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Keywords | RNA / G2C4 repeats / ALS / FTD / hexanucleotide repeats |