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TitleCachd1 interacts with Wnt receptors and regulates neuronal asymmetry in the zebrafish brain.
Journal, issue, pagesScience, Vol. 384, Page 573-579, Year 2024
Publish dateFeb 29, 2024 (structure data deposition date)
AuthorsPowell, G.T. / Faro, A. / Zhao, Y. / Stickney, H. / Novellasdemunt, L. / Henriques, P. / Gestri, G. / Redhouse White, E. / Ren, J. / Lu, W. ...Powell, G.T. / Faro, A. / Zhao, Y. / Stickney, H. / Novellasdemunt, L. / Henriques, P. / Gestri, G. / Redhouse White, E. / Ren, J. / Lu, W. / Young, R.M. / Hawkins, T.A. / Cavodeassi, F. / Schwarz, Q. / Dreosti, E. / Raible, D.W. / Li, V.S.W. / Wright, G.J. / Jones, E.Y. / Wilson, S.W.
External linksScience / PubMed:38696577
MethodsX-ray diffraction
Resolution2.72 - 4.7 Å
Structure data

PDB-8s7c:
Ternary Complex of Cachd1, FZD5 and LRP6
Method: X-RAY DIFFRACTION / Resolution: 4.7 Å

PDB-9eq6:
Cachd1 and FZD5 complex
Method: X-RAY DIFFRACTION / Resolution: 2.72 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
  • homo sapiens (human)
KeywordsSIGNALING PROTEIN / Cachd1 Frizzled-5 LRP6

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