タイトル | The C-terminal Region of D-DT Regulates Molecular Recognition for Protein-Ligand Complexes. |
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ジャーナル・号・ページ | J. Med. Chem., Vol. 67, Page 7359-7372, Year 2024 |
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掲載日 | 2023年12月18日 (構造データの登録日) |
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著者 | Parkins, A. / Pilien, A.V.R. / Wolff, A.M. / Argueta, C. / Vargas, J. / Sadeghi, S. / Franz, A.H. / Thompson, M.C. / Pantouris, G. |
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リンク | J. Med. Chem. / PubMed:38670943 |
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手法 | X線回折 |
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解像度 | 1.23 - 2.44 Å |
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構造データ | PDB-8vdy: Crystal Structure of Delta 114-117 D-Dopachrome Tautomerase (D-DT) 手法: X-RAY DIFFRACTION / 解像度: 2.44 Å PDB-8vfk: Crystal Structure of Delta 109-117 D-Dopachrome Tautomerase (D-DT) 手法: X-RAY DIFFRACTION / 解像度: 1.59 Å PDB-8vfl: Crystal Structure of WT D-Dopachrome Tautomerase (D-DT) at 290K 手法: X-RAY DIFFRACTION / 解像度: 1.23 Å PDB-8vfn: Crystal Structure of WT D-Dopachrome Tautomerase (D-DT) at 310K 手法: X-RAY DIFFRACTION / 解像度: 1.29 Å PDB-8vfo: Crystal Structure of L117G Variant of D-Dopachrome Tautomerase (D-DT) 手法: X-RAY DIFFRACTION / 解像度: 1.35 Å PDB-8vfw: Crystal Structure of V113N D-Dopachrome Tautomerase (D-DT) 手法: X-RAY DIFFRACTION / 解像度: 1.31 Å PDB-8vg5: Crystal Structure of V113N Variant of D-Dopachrome Tautomerase (D-DT) Bound with 4CPPC 手法: X-RAY DIFFRACTION / 解像度: 1.5 Å PDB-8vg7: Crystal Structure of T115A Variant of D-Dopachrome Tautomerase (D-DT) 手法: X-RAY DIFFRACTION / 解像度: 1.24 Å PDB-8vg8: Crystal Structure of T115A Variant of D-Dopachrome Tautomerase (D-DT) Bound to 4CPPC 手法: X-RAY DIFFRACTION / 解像度: 1.33 Å |
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化合物 | ChemComp-7L9: 4-(3-carboxyphenyl)pyridine-2,5-dicarboxylic acid
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由来 | - homo sapiens (ヒト)
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キーワード | ISOMERASE / Truncation / Enzyme / Cytokine |
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