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TitleAn unusual aromatase/cyclase programs the formation of the phenyldimethylanthrone framework in anthrabenzoxocinones and fasamycin.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 121, Page e2321722121-e2321722121, Year 2024
Publish dateMar 20, 2023 (structure data deposition date)
AuthorsJiang, K. / Chen, X. / Yan, X. / Li, G. / Lin, Z. / Deng, Z. / Luo, S. / Qu, X.
External linksProc. Natl. Acad. Sci. USA / PubMed:38446858
MethodsX-ray diffraction
Resolution1.32 Å
Structure data

PDB-8is2:
Crystal structure of a polyketide aromatase/cyclase Abx(+)D from Actinomycetes sp. MA7150.
Method: X-RAY DIFFRACTION / Resolution: 1.32 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • uncultured actinomycete (environmental samples)
KeywordsBIOSYNTHETIC PROTEIN / aromatase / cyclase / polyketide

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