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TitleStructure-guided engineering enables E3 ligase-free and versatile protein ubiquitination via UBE2E1.
Journal, issue, pagesNat Commun, Vol. 15, Page 1266-1266, Year 2024
Publish dateApr 4, 2023 (structure data deposition date)
AuthorsWu, X. / Du, Y. / Liang, L.J. / Ding, R. / Zhang, T. / Cai, H. / Tian, X. / Pan, M. / Liu, L.
External linksNat Commun / PubMed:38341401
MethodsX-ray diffraction
Resolution2.43 Å
Structure data

PDB-8iya:
Complex of SETDB1-derived peptide bound to UBE2E1
Method: X-RAY DIFFRACTION / Resolution: 2.43 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsPROTEIN BINDING / Ubiquitin / Recognition / Conjugation

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