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TitleUnusual Base Pair between Two 2-Thiouridines and Its Implication for Nonenzymatic RNA Copying.
Journal, issue, pagesJ. Am. Chem. Soc., Vol. 146, Page 3861-3871, Year 2024
Publish dateDec 6, 2022 (structure data deposition date)
AuthorsDing, D. / Fang, Z. / Kim, S.C. / O'Flaherty, D.K. / Jia, X. / Stone, T.B. / Zhou, L. / Szostak, J.W.
External linksJ. Am. Chem. Soc. / PubMed:38293747
MethodsX-ray diffraction
Resolution1.5 - 1.55 Å
Structure data

PDB-8feo:
16mer self-complementary duplex RNA with two separated native U:U pairs
Method: X-RAY DIFFRACTION / Resolution: 1.52 Å

PDB-8fep:
16mer self-complementary duplex RNA with two continuous native U:U pairs
Method: X-RAY DIFFRACTION / Resolution: 1.55 Å

PDB-8feq:
16mer self-complementary duplex RNA with two separated s(2)U:s(2)U pairs
Method: X-RAY DIFFRACTION / Resolution: 1.5 Å

PDB-8fer:
16mer self-complementary duplex RNA with two continuous s(2)U:s(2)U pairs
Method: X-RAY DIFFRACTION / Resolution: 1.54 Å

Chemicals

ChemComp-SR:
STRONTIUM ION

ChemComp-MG:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-CA:
Unknown entry

Source
  • synthetic construct (others)
KeywordsRNA / Duplexes / UU pairs / 2-thio-U

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