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Structure paper

TitleStructural insights into the specific recognition of mitochondrial ribosome-binding factor hsRBFA and 12 S rRNA by methyltransferase METTL15.
Journal, issue, pagesCell Discov, Vol. 10, Page 11-11, Year 2024
Publish dateMar 14, 2023 (structure data deposition date)
AuthorsLv, M. / Zhou, W. / Hao, Y. / Li, F. / Zhang, H. / Yao, X. / Shi, Y. / Zhang, L.
External linksCell Discov / PubMed:38291322
MethodsX-ray diffraction
Resolution1.9 - 3.1 Å
Structure data

PDB-8ipi:
The apo structure of human mitochondrial methyltransferase METTL15
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

PDB-8ipk:
The structure of human mitochondrial methyltransferase METTL15 with SAM
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

PDB-8ipl:
The structure of human mitochondrial methyltransferase METTL15 with RBFA and SAM
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

PDB-8ipm:
The structure of human mitochondrial methyltransferase METTL15 with h44_RNA, RBFA and SAM
Method: X-RAY DIFFRACTION / Resolution: 3.1 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-SAM:
S-ADENOSYLMETHIONINE

ChemComp-GOL:
GLYCEROL

ChemComp-SFG:
SINEFUNGIN

Source
  • homo sapiens (human)
KeywordsRIBOSOMAL PROTEIN / human mitochondrial methyltransferase METTL15

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