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TitleBiochemical and Structural Analysis of the Bacterial Enzyme Succinyl-Diaminopimelate Desuccinylase (DapE) from Acinetobacter baumannii.
Journal, issue, pagesAcs Omega, Vol. 9, Page 3905-3915, Year 2024
Publish dateDec 2, 2021 (structure data deposition date)
AuthorsKelley, E.H. / Minasov, G. / Konczak, K. / Shuvalova, L. / Brunzelle, J.S. / Shukla, S. / Beulke, M. / Thabthimthong, T. / Olsen, K.W. / Inniss, N.L. ...Kelley, E.H. / Minasov, G. / Konczak, K. / Shuvalova, L. / Brunzelle, J.S. / Shukla, S. / Beulke, M. / Thabthimthong, T. / Olsen, K.W. / Inniss, N.L. / Satchell, K.J.F. / Becker, D.P.
External linksAcs Omega / PubMed:38284080
MethodsX-ray diffraction
Resolution2.1 - 2.25 Å
Structure data

PDB-7t1q:
Crystal Structure of the Succinyl-diaminopimelate Desuccinylase (DapE) from Acinetobacter baumannii in complex with Succinic Acid
Method: X-RAY DIFFRACTION / Resolution: 2.25 Å

PDB-8f8o:
Crystal Structure of the Succinyl-diaminopimelate Desuccinylase (DapE) from Acinetobacter baumannii in complex with Succinic and L-Lactic Acids
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

Chemicals

ChemComp-SIN:
SUCCINIC ACID

ChemComp-ACT:
ACETATE ION

ChemComp-PGE:
TRIETHYLENE GLYCOL

ChemComp-ZN:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-2OP:
(2S)-2-HYDROXYPROPANOIC ACID

ChemComp-PG4:
TETRAETHYLENE GLYCOL / precipitant*YM

ChemComp-CIT:
CITRIC ACID

Source
  • acinetobacter baumannii atcc 17978 (bacteria)
KeywordsHYDROLASE / Structural Genomics / Center for Structural Genomics of Infectious Diseases / CSGID / DapE / Center for Structural Biology of Infectious Diseases (CSBID) / Succinate / L-Lactate

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