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Structure paper

TitleUBE2A and UBE2B are recruited by an atypical E3 ligase module in UBR4.
Journal, issue, pagesNat. Struct. Mol. Biol., Vol. 31, Page 351-363, Year 2024
Publish dateSep 24, 2022 (structure data deposition date)
AuthorsBarnsby-Greer, L. / Mabbitt, P.D. / Dery, M.A. / Squair, D.R. / Wood, N.T. / Lamoliatte, F. / Lange, S.M. / Virdee, S.
External linksNat. Struct. Mol. Biol. / PubMed:38182926
MethodsX-ray diffraction
Resolution1.8 - 3.2 Å
Structure data

PDB-8b5w:
Crystal structure of the E3 module from UBR4
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

PDB-8btl:
Crystal structure of a complex between the E2 conjugating enzyme UBE2A and the E3 ligase module from UBR4
Method: X-RAY DIFFRACTION / Resolution: 3.2 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsLIGASE / ubiquitin / E3 ligase / zinc finger / E2 conjugating enzyme

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