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Structure paper

TitleA protective and broadly binding antibody class engages the influenza virus hemagglutinin head at its stem interface.
Journal, issue, pagesBiorxiv, Year 2024
Publish dateOct 27, 2023 (structure data deposition date)
AuthorsSimmons, H.C. / Finney, J. / Kotaki, R. / Adachi, Y. / Park Moseman, A. / Watanabe, A. / Song, S. / Robinson-McCarthy, L.R. / Le Sage, V. / Kuraoka, M. ...Simmons, H.C. / Finney, J. / Kotaki, R. / Adachi, Y. / Park Moseman, A. / Watanabe, A. / Song, S. / Robinson-McCarthy, L.R. / Le Sage, V. / Kuraoka, M. / Moseman, E.A. / Kelsoe, G. / Takahashi, Y. / McCarthy, K.R.
External linksBiorxiv / PubMed:38168412
MethodsX-ray diffraction
Resolution3.7 Å
Structure data

PDB-8us0:
Human antibody S8V1-157 in complex with the A/American black duck/New Brunswick/00464/2010(H4N6) HA head domain
Method: X-RAY DIFFRACTION / Resolution: 3.7 Å

Chemicals

ChemComp-MES:
2-(N-MORPHOLINO)-ETHANESULFONIC ACID / pH buffer*YM

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

Source
  • influenza a virus
  • homo sapiens (human)
KeywordsViral Protein/IMMUNE SYSTEM / virus / antibody / influenza / fab / fragment antigen-binding / protection / IMMUNE SYSTEM / Viral Protein-IMMUNE SYSTEM complex

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