タイトル | A single C-terminal residue controls SARS-CoV-2 spike trafficking and incorporation into VLPs. |
---|
ジャーナル・号・ページ | Nat Commun, Vol. 14, Page 8358-8358, Year 2023 |
---|
掲載日 | 2022年9月30日 (構造データの登録日) |
---|
著者 | Dey, D. / Qing, E. / He, Y. / Chen, Y. / Jennings, B. / Cohn, W. / Singh, S. / Gakhar, L. / Schnicker, N.J. / Pierce, B.G. ...Dey, D. / Qing, E. / He, Y. / Chen, Y. / Jennings, B. / Cohn, W. / Singh, S. / Gakhar, L. / Schnicker, N.J. / Pierce, B.G. / Whitelegge, J.P. / Doray, B. / Orban, J. / Gallagher, T. / Hasan, S.S. |
---|
リンク | Nat Commun / PubMed:38102143 |
---|
手法 | X線回折 |
---|
解像度 | 1.45 - 2 Å |
---|
構造データ | PDB-8ens: Crystal structure of beta'-COPI-WD40 domain in complex with SARS-CoV-2 spike tail hepta-peptide 手法: X-RAY DIFFRACTION / 解像度: 1.45 Å PDB-8enw: Crystal structure of beta'-COPI-WD40 domain in complex with SARS-CoV-2 clientized spike tail heptapeptide. 手法: X-RAY DIFFRACTION / 解像度: 1.45 Å PDB-8enx: Crystal structure of beta'-COPI-WD40 domain Y33A mutant in complex with SARS-CoV-2 clientized spike tail heptapeptide. 手法: X-RAY DIFFRACTION / 解像度: 1.8 Å PDB-8eny: Crystal structure of alpha-COPI-WD40 domain R13A mutant. 手法: X-RAY DIFFRACTION / 解像度: 1.9 Å PDB-8enz: Crystal structure of alpha-COPI-WD40 domain K15A mutant. 手法: X-RAY DIFFRACTION / 解像度: 1.65 Å PDB-8eo0: Crystal structure of alpha-COPI WD40 domain R300A mutant. 手法: X-RAY DIFFRACTION / 解像度: 1.8 Å PDB-8szx: Crystal structure of b'-WD40 Lys17Ala mutant 手法: X-RAY DIFFRACTION / 解像度: 2 Å |
---|
化合物 | |
---|
由来 | ![](img/tx_yeast.gif) saccharomyces cerevisiae (パン酵母)![](img/tx_virus.gif) severe acute respiratory syndrome coronavirus 2 (ウイルス)![](img/tx_yeast.gif) schizosaccharomyces pombe (分裂酵母)
|
---|
キーワード | PROTEIN TRANSPORT / COPI / protein trafficking / SARS-CoV-2 spike / dibasic motif |
---|