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-Structure paper
Title | A unique binding pocket induced by a noncanonical SAH mimic to develop potent and selective PRMT inhibitors. |
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Journal, issue, pages | Acta Pharm Sin B, Vol. 13, Page 4893-4905, Year 2023 |
Publish date | Feb 3, 2023 (structure data deposition date) |
Authors | Deng, Y. / Song, X. / Iyamu, I.D. / Dong, A. / Min, J. / Huang, R. |
External links | Acta Pharm Sin B / PubMed:38045046 |
Methods | X-ray diffraction |
Resolution | 1.49 - 2.17 Å |
Structure data | PDB-8g2f: PDB-8g2g: PDB-8g2h: PDB-8g2i: |
Chemicals | ChemComp-DVS: ChemComp-HOH: ChemComp-YVU: ChemComp-SO4: ChemComp-GOL: ChemComp-NA: ChemComp-UNX:
ChemComp-I0B: |
Source |
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Keywords | TRANSFERASE/INHIBITOR / PRMT3 / II710 / TRANSFERASE / Structural Genomics / PSI-2 / Protein Structure Initiative / Structural Genomics Consortium / SGC / TRANSFERASE-INHIBITOR complex / YD1113 / PRMT4 / YD1290 |