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Structure paper

TitleDissection of integrated readout reveals the structural thermodynamics of DNA selection by transcription factors.
Journal, issue, pagesStructure, Vol. 32, Page 83-96.e4, Year 2024
Publish dateApr 26, 2023 (structure data deposition date)
AuthorsVernon, T.N. / Terrell, J.R. / Albrecht, A.V. / Germann, M.W. / Wilson, W.D. / Poon, G.M.K.
External linksStructure / PubMed:38042148
MethodsX-ray diffraction
Resolution1.37 - 1.62 Å
Structure data

PDB-8smh:
Chimeric ETS-domain of murine PU.1 harboring the corresponding beta-strand 3 (S3) residues from murine Ets-1 in complex with d(AATAAGCGGAAGTGGG)
Method: X-RAY DIFFRACTION / Resolution: 1.37 Å

PDB-8smj:
Chimeric ETS-domain of murine PU.1 harboring the corresponding beta-strand 3 (S3) residues from murine Ets-1 in complex with d(AATAAGCGGAATGGGG)
Method: X-RAY DIFFRACTION / Resolution: 1.39 Å

PDB-8sp1:
Chimeric ETS-domain of murine PU.1 harboring the corresponding beta-strand 3 (S3) residues from murine Ets-1 in complex with d(AATAAGCGIAAGTGGG)
Method: X-RAY DIFFRACTION / Resolution: 1.62 Å

PDB-8t9u:
Human PU.1 ETS-domain (165-270) in complex with d(AATAAGCGIAAGTGGG)
Method: X-RAY DIFFRACTION / Resolution: 1.47 Å

Chemicals

ChemComp-NA:
Unknown entry

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
  • synthetic construct (others)
  • homo sapiens (human)
  • dna molecule (others)
KeywordsTRANSCRIPTION / transcription factor / protein-DNA complex / ETS family / ETS / PU.1 / TRANSCRIPTION-DNA complex / TRANSCRIPTION/DNA

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