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TitleA simple method for developing lysine targeted covalent protein reagents.
Journal, issue, pagesNat Commun, Vol. 14, Page 7933-7933, Year 2023
Publish dateDec 22, 2022 (structure data deposition date)
AuthorsGabizon, R. / Tivon, B. / Reddi, R.N. / van den Oetelaar, M.C.M. / Amartely, H. / Cossar, P.J. / Ottmann, C. / London, N.
External linksNat Commun / PubMed:38040731
MethodsX-ray diffraction
Resolution2.2 - 2.3 Å
Structure data

PDB-8c2e:
Structure of 14-3-3 sigma delta C with electrophilic peptide 4IEA-5
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

PDB-8c2f:
Structure of 14-3-3 sigma delta C with electrophilic peptide 3MHR-5
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

Chemicals

ChemComp-TJI:
ethyl 3-bromanyl-2-methyl-propanoate

ChemComp-MG:
Unknown entry

ChemComp-CL:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsPROTEIN BINDING / 14-3-3 sigma / 4IEA-5 / covalent / 3MHR-5

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