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TitleTargeting the Structural Maturation Pathway of HIV-1 Reverse Transcriptase.
Journal, issue, pagesBiomolecules, Vol. 13, Year 2023
Publish dateJul 2, 2023 (structure data deposition date)
AuthorsKirby, T.W. / Gabel, S.A. / DeRose, E.F. / Perera, L. / Krahn, J.M. / Pedersen, L.C. / London, R.E.
External linksBiomolecules / PubMed:38002285
MethodsX-ray diffraction
Resolution1.82 - 2.2 Å
Structure data

PDB-8tcj:
Apo crystal Structure of modified HIV reverse transcriptase p51 domain (FPC2)
Method: X-RAY DIFFRACTION / Resolution: 1.848 Å

PDB-8tck:
Apo crystal Structure of modified HIV reverse transcriptase p51 domain (FPC1)
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

PDB-8tcl:
Crystal Structure of modified HIV reverse transcriptase p51 domain (FPC2) with picrate bound
Method: X-RAY DIFFRACTION / Resolution: 1.95 Å

PDB-8tcm:
Crystal Structure of modified HIV reverse transcriptase p51 domain (FPC1) with picric acid and Xanthene-1,3,6,8-tetrol bound
Method: X-RAY DIFFRACTION / Resolution: 1.82 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-TNF:
PICRIC ACID


ChemComp, No image

ChemComp-ZQT:
Unknown entry

Source
  • hiv whole-genome vector aa1305#18 (others)
KeywordsDNA BINDING PROTEIN / P51 subunit / HIV / AIDS / transferase / picric acid / Xanthene-1 / 3 / 6 / 8-tetrol

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