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Structure paper

TitleStructural analysis of PLD3 reveals insights into the mechanism of lysosomal 5' exonuclease-mediated nucleic acid degradation.
Journal, issue, pagesNucleic Acids Res., Vol. 52, Page 370-384, Year 2024
Publish dateJul 31, 2023 (structure data deposition date)
AuthorsRoske, Y. / Cappel, C. / Cremer, N. / Hoffmann, P. / Koudelka, T. / Tholey, A. / Heinemann, U. / Daumke, O. / Damme, M.
External linksNucleic Acids Res. / PubMed:37994783
MethodsX-ray diffraction
Resolution1.51 - 1.85 Å
Structure data

PDB-8q1k:
Structural analysis of PLD3 reveals insights into the mechanism of lysosomal 5' exonuclease-mediated nucleic acid degradation
Method: X-RAY DIFFRACTION / Resolution: 1.51 Å

PDB-8q1x:
Structural analysis of PLD3 reveals insights into the mechanism of lysosomal 5' exonuclease-mediated nucleic acid degradation
Method: X-RAY DIFFRACTION / Resolution: 1.85 Å

Chemicals

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-PO4:
PHOSPHATE ION

ChemComp-MN:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-PST:
THYMIDINE-5'-THIOPHOSPHATE

ChemComp-SO4:
SULFATE ION

ChemComp-MG:
Unknown entry

Source
  • homo sapiens (human)
KeywordsDNA BINDING PROTEIN / PLD3 / structural biology / lysosome / DNA/RNA degradation / phospholipase D / 5' exonuclease

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