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TitleFormaldehyde regulates S -adenosylmethionine biosynthesis and one-carbon metabolism.
Journal, issue, pagesScience, Vol. 382, Page eabp9201-eabp9201, Year 2023
Publish dateMay 18, 2023 (structure data deposition date)
AuthorsPham, V.N. / Bruemmer, K.J. / Toh, J.D.W. / Ge, E.J. / Tenney, L. / Ward, C.C. / Dingler, F.A. / Millington, C.L. / Garcia-Prieto, C.A. / Pulos-Holmes, M.C. ...Pham, V.N. / Bruemmer, K.J. / Toh, J.D.W. / Ge, E.J. / Tenney, L. / Ward, C.C. / Dingler, F.A. / Millington, C.L. / Garcia-Prieto, C.A. / Pulos-Holmes, M.C. / Ingolia, N.T. / Pontel, L.B. / Esteller, M. / Patel, K.J. / Nomura, D.K. / Chang, C.J.
External linksScience / PubMed:37917677
MethodsX-ray diffraction
Resolution1.999 Å
Structure data

PDB-8swa:
Crystal structure of the human S-adenosylmethionine synthetase 1 in complex with SAM and PPNP
Method: X-RAY DIFFRACTION / Resolution: 1.999 Å

Chemicals

ChemComp-PPK:
(DIPHOSPHONO)AMINOPHOSPHONIC ACID

ChemComp-MG:
Unknown entry

ChemComp-K:
Unknown entry

ChemComp-SAM:
S-ADENOSYLMETHIONINE

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / Complex / 1-carbon / SAM

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