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-Structure paper
Title | A Mechanistic Understanding of the Distinct Regio- and Chemoselectivity of Multifunctional P450s by Structural Comparison of IkaD and CftA Complexed with Common Substrates. |
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Journal, issue, pages | Angew. Chem. Int. Ed. Engl., Vol. 62, Page e202310728-e202310728, Year 2023 |
Publish date | Jun 6, 2023 (structure data deposition date) |
![]() | Jiang, P. / Jin, H. / Zhang, G. / Zhang, W. / Liu, W. / Zhu, Y. / Zhang, C. / Zhang, L. |
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Methods | X-ray diffraction |
Resolution | 2 - 2.25 Å |
Structure data | ![]() PDB-8jnc: ![]() PDB-8jno: ![]() PDB-8jnp: ![]() PDB-8jnq: ![]() PDB-8joo: ![]() PDB-8jua: |
Chemicals | ![]() ChemComp-HEM: ![]() ChemComp-E5I: ![]() ChemComp-FMT: ![]() ChemComp-NA: ![]() ChemComp-HOH: ![]() ChemComp-E8T: ![]() ChemComp-EIA: ![]() ChemComp-EIU: ![]() ChemComp-F7Z: |
Source |
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![]() | OXIDOREDUCTASE / hydroxylation / polycyclic tetramate macrolactam / cytochrome P450 / Actinomadura viridis / hydrolase / Lobophorin / deglycosylation / C-H functionalization / regioselectivity / chemoselectivity / polycyclic tetramate macrolactam (PoTeM) / cytochrome P450 enzyme |