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TitleCrystal Structure of DNA Replication Protein SsbA Complexed with the Anticancer Drug 5-Fluorouracil.
Journal, issue, pagesInt J Mol Sci, Vol. 24, Year 2023
Publish dateJul 27, 2022 (structure data deposition date)
AuthorsSu, H.H. / Huang, Y.H. / Lien, Y. / Yang, P.C. / Huang, C.Y.
External linksInt J Mol Sci / PubMed:37834349
MethodsX-ray diffraction
Resolution1.8 - 2.36 Å
Structure data

PDB-7ym1:
Structure of SsbA protein in complex with the anticancer drug 5-fluorouracil
Method: X-RAY DIFFRACTION / Resolution: 2.36 Å

PDB-8gw5:
Crystal structure of SaSsbA complexed with glycerol
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

Chemicals

ChemComp-URF:
5-FLUOROURACIL / medication, chemotherapy*YM

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • staphylococcus aureus subsp. aureus ed98 (bacteria)
KeywordsDNA BINDING PROTEIN / single-strand DNA binding protein

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