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Structure paper

TitleBiochemical and biophysical characterization of natural polyreactivity in antibodies.
Journal, issue, pagesCell Rep, Vol. 42, Page 113190-113190, Year 2023
Publish dateJan 29, 2023 (structure data deposition date)
AuthorsBorowska, M.T. / Boughter, C.T. / Bunker, J.J. / Guthmiller, J.J. / Wilson, P.C. / Roux, B. / Bendelac, A. / Adams, E.J.
External linksCell Rep / PubMed:37804505
MethodsX-ray diffraction
Resolution1.63 - 1.83 Å
Structure data

PDB-8fzo:
Crystal structure of polyreactive 338E6 mouse Fab
Method: X-RAY DIFFRACTION / Resolution: 1.83 Å

PDB-8fzp:
Crystal structure of polyreactive 43G10 mouse Fab
Method: X-RAY DIFFRACTION / Resolution: 1.63 Å

PDB-8g19:
Crystal structure of monoreactive 4C05 human Fab
Method: X-RAY DIFFRACTION / Resolution: 1.77 Å

PDB-8g1b:
Crystal structure of polyreactive 2G02 human Fab
Method: X-RAY DIFFRACTION / Resolution: 1.67 Å

PDB-8g1c:
Crystal structure of polyreactive 3B03 human Fab
Method: X-RAY DIFFRACTION / Resolution: 1.63 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / Polyreactivity / Polyspecificity / Fab / Immunoglobulin A / immunoglobulin G / anti-influenza / monoreactive

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