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TitleRiPP enzyme heterocomplex structure-guided discovery of a bacterial borosin alpha- N -methylated peptide natural product.
Journal, issue, pagesRsc Chem Biol, Vol. 4, Page 804-816, Year 2023
Publish dateJun 3, 2023 (structure data deposition date)
AuthorsCrone, K.K. / Jomori, T. / Miller, F.S. / Gralnick, J.A. / Elias, M.H. / Freeman, M.F.
External linksRsc Chem Biol / PubMed:37799586
MethodsX-ray diffraction
Resolution1.55 - 2 Å
Structure data

PDB-8t1s:
Structure of the alpha-N-methyltransferase (SonM) and RiPP precursor (SonA with QSY deletion) heteromeric complex (bound to SAH)
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-8t1t:
Structure of the alpha-N-methyltransferase (SonM) and RiPP precursor (SonA with QSY deletion) heteromeric complex (bound to SAM)
Method: X-RAY DIFFRACTION / Resolution: 1.55 Å

Chemicals

ChemComp-SAH:
S-ADENOSYL-L-HOMOCYSTEINE

ChemComp-ZN:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-SAM:
S-ADENOSYLMETHIONINE

Source
  • shewanella oneidensis (bacteria)
KeywordsTRANSFERASE / alpha-N-methyltransferase / borosin / natural products. / natural products

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