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Structure paper

TitleAnti-InlA single-domain antibodies that inhibit the cell invasion of Listeria monocytogenes.
Journal, issue, pagesJ. Biol. Chem., Vol. 299, Page 105254-105254, Year 2023
Publish dateOct 14, 2022 (structure data deposition date)
AuthorsYamazaki, T. / Nagatoishi, S. / Yamawaki, T. / Nozawa, T. / Matsunaga, R. / Nakakido, M. / Caaveiro, J.M.M. / Nakagawa, I. / Tsumoto, K.
External linksJ. Biol. Chem. / PubMed:37716701
MethodsX-ray diffraction
Resolution1.53 - 2.35 Å
Structure data

PDB-8h62:
Crystal structure of Internalin A from Listeria monocytogenes with human E-cadherin EC12
Method: X-RAY DIFFRACTION / Resolution: 1.91 Å

PDB-8h63:
Crystal structure of Internalin A from Listeria monocytogenes with nanobody VHH10 bound
Method: X-RAY DIFFRACTION / Resolution: 1.53 Å

PDB-8h64:
Crystal structure of Internalin A from Listeria monocytogenes with nanobody VHH24 bound
Method: X-RAY DIFFRACTION / Resolution: 2.35 Å

Chemicals

ChemComp-CA:
Unknown entry

ChemComp-ACT:
ACETATE ION

ChemComp-HOH:
WATER

ChemComp-EPE:
4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID / pH buffer*YM

ChemComp-IPA:
ISOPROPYL ALCOHOL / alkaloid*YM

ChemComp-GOL:
GLYCEROL

ChemComp-NA:
Unknown entry

ChemComp-CL:
Unknown entry

Source
  • listeria monocytogenes serovar 1/2a (bacteria)
  • homo sapiens (human)
  • lama glama (llama)
KeywordsCELL INVASION / Internalin A Cadherin Bacterial invasion nanobody Surface plasmon resonance Isothermal titration calorimetry / CELL INVASION/IMMUNE SYSTEM / CELL INVASION-IMMUNE SYSTEM complex

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