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TitleNucleoside diphosphate kinases 1 and 2 regulate a protective liver response to a high-fat diet.
Journal, issue, pagesSci Adv, Vol. 9, Page eadh0140-eadh0140, Year 2023
Publish dateApr 14, 2022 (structure data deposition date)
AuthorsIuso, D. / Garcia-Saez, I. / Coute, Y. / Yamaryo-Botte, Y. / Boeri Erba, E. / Adrait, A. / Zeaiter, N. / Tokarska-Schlattner, M. / Jilkova, Z.M. / Boussouar, F. ...Iuso, D. / Garcia-Saez, I. / Coute, Y. / Yamaryo-Botte, Y. / Boeri Erba, E. / Adrait, A. / Zeaiter, N. / Tokarska-Schlattner, M. / Jilkova, Z.M. / Boussouar, F. / Barral, S. / Signor, L. / Couturier, K. / Hajmirza, A. / Chuffart, F. / Bourova-Flin, E. / Vitte, A.L. / Bargier, L. / Puthier, D. / Decaens, T. / Rousseaux, S. / Botte, C. / Schlattner, U. / Petosa, C. / Khochbin, S.
External linksSci Adv / PubMed:37672589
MethodsX-ray diffraction
Resolution1.96 - 2.6 Å
Structure data

PDB-7zl8:
NME1 in complex with succinyl-CoA
Method: X-RAY DIFFRACTION / Resolution: 1.96 Å

PDB-7zlw:
NME1 in complex with ADP
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

PDB-7ztk:
NME1 in complex with CoA
Method: X-RAY DIFFRACTION / Resolution: 2.6 Å

Chemicals

ChemComp-SCA:
SUCCINYL-COENZYME A

ChemComp-HOH:
WATER

ChemComp-ADP:
ADENOSINE-5'-DIPHOSPHATE / ADP, energy-carrying molecule*YM

ChemComp-COA:
COENZYME A

Source
  • mus musculus (house mouse)
KeywordsTRANSFERASE / NME1 / complex / nucleoside diphosphate kinase 1 / succinyl-CoA / ADP / coenzyme-A

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