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Title | Discovery and multimerization of cross-reactive single-domain antibodies against SARS-like viruses to enhance potency and address emerging SARS-CoV-2 variants. |
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Journal, issue, pages | Sci Rep, Vol. 13, Page 13668-13668, Year 2023 |
Publish date | Apr 18, 2023 (structure data deposition date) |
Authors | Hollingsworth, S.A. / Noland, C.L. / Vroom, K. / Saha, A. / Sam, M. / Gao, Q. / Zhou, H. / Grandy, D.U. / Singh, S. / Wen, Z. ...Hollingsworth, S.A. / Noland, C.L. / Vroom, K. / Saha, A. / Sam, M. / Gao, Q. / Zhou, H. / Grandy, D.U. / Singh, S. / Wen, Z. / Warren, C. / Ma, X.S. / Malashock, D. / Galli, J. / Go, G. / Eddins, M. / Mayhood, T. / Sathiyamoorthy, K. / Fridman, A. / Raoufi, F. / Gomez-Llorente, Y. / Patridge, A. / Tang, Y. / Chen, S.J. / Bailly, M. / Ji, C. / Kingsley, L.J. / Cheng, A.C. / Geierstanger, B.H. / Gorman, D.M. / Zhang, L. / Pande, K. |
External links | Sci Rep / PubMed:37608223 |
Methods | X-ray diffraction |
Resolution | 2.011 Å |
Structure data | PDB-8sk5: |
Chemicals | ChemComp-HOH: |
Source |
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Keywords | ANTIVIRAL PROTEIN / VHH / Complex |