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TitleMechanism of the extremely high duplex-forming ability of oligonucleotides modified with N-tert-butylguanidine- or N-tert-butyl-N'- methylguanidine-bridged nucleic acids.
Journal, issue, pagesNucleic Acids Res., Vol. 51, Page 7749-7761, Year 2023
Publish dateNov 21, 2022 (structure data deposition date)
AuthorsYamaguchi, T. / Horie, N. / Aoyama, H. / Kumagai, S. / Obika, S.
External linksNucleic Acids Res. / PubMed:37462081
MethodsX-ray diffraction
Resolution0.93 - 2.01 Å
Structure data

PDB-8his:
Crystal structure of DNA decamer containing GuNA[Me,tBu]
Method: X-RAY DIFFRACTION / Resolution: 2.01 Å

PDB-8hu5:
Crystal structure of DNA octamer containing GuNA[Me,tBu]
Method: X-RAY DIFFRACTION / Resolution: 0.93 Å

PDB-8i50:
Crystal structure of DNA octamer containing GuNA[Me,Me]
Method: X-RAY DIFFRACTION / Resolution: 0.95 Å

Chemicals

ChemComp-CAD:
CACODYLIC ACID

ChemComp-HOH:
WATER

Source
  • synthetic construct (others)
KeywordsDNA / OLIGONUCLEOTIDE / MODIFIED BASE / Artificial nucleic acid

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