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TitleIdentification of Regulatory Molecular "Hot Spots" for LH/PLOD Collagen Glycosyltransferase Activity.
Journal, issue, pagesInt J Mol Sci, Vol. 24, Year 2023
Publish dateApr 2, 2023 (structure data deposition date)
AuthorsMattoteia, D. / Chiapparino, A. / Fumagalli, M. / De Marco, M. / De Giorgi, F. / Negro, L. / Pinnola, A. / Faravelli, S. / Roscioli, T. / Scietti, L. / Forneris, F.
External linksInt J Mol Sci / PubMed:37446392
MethodsX-ray diffraction
Resolution2.3 Å
Structure data

PDB-8one:
Crystal Structure of full-length Human Lysyl Hydroxylase LH3 - Asp190Ser mutant - Cocrystal with Fe2+, Mn2+, UDP-Glucose
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

Chemicals

ChemComp-AKG:
2-OXOGLUTARIC ACID

ChemComp-FE2:
Unknown entry

ChemComp-MN:
Unknown entry

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-GOL:
GLYCEROL

ChemComp-UPG:
URIDINE-5'-DIPHOSPHATE-GLUCOSE

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / Collagen biosynthesis; extracellular matrix; post-translational modifications; collagen glycosylations; glycosyltransferase; lysyl hydroxylase

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