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Structure paper

TitleStructural insights into CodY activation and DNA recognition.
Journal, issue, pagesNucleic Acids Res., Vol. 51, Page 7631-7648, Year 2023
Publish dateJan 16, 2023 (structure data deposition date)
AuthorsHainzl, T. / Bonde, M. / Almqvist, F. / Johansson, J. / Sauer-Eriksson, A.E.
External linksNucleic Acids Res. / PubMed:37326020
MethodsX-ray diffraction
Resolution2.05 - 3.15 Å
Structure data

PDB-8c7o:
Unliganded transcriptional pleiotropic repressor CodY from Staphylococcus aureus
Method: X-RAY DIFFRACTION / Resolution: 2.05 Å

PDB-8c7s:
Transcriptional pleiotropic repressor CodY from Staphylococcus aureus in complex with Ile, GTP, and a 30-bp DNA fragment encompassing two overlapping binding sites
Method: X-RAY DIFFRACTION / Resolution: 3.05 Å

PDB-8c7t:
Unliganded transcriptional pleiotropic repressor CodY from Enterococcus faecalis
Method: X-RAY DIFFRACTION / Resolution: 2.21 Å

PDB-8c7u:
Transcriptional pleiotropic repressor CodY from Enterococcus faecalis in complex with Leu and a 30-bp DNA fragment encompassing two overlapping binding sites
Method: X-RAY DIFFRACTION / Resolution: 3.15 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-ACT:
ACETATE ION

ChemComp-HOH:
WATER

ChemComp-GTP:
GUANOSINE-5'-TRIPHOSPHATE / GTP, energy-carrying molecule*YM

ChemComp-ILE:
ISOLEUCINE

ChemComp-LEU:
LEUCINE

ChemComp-MN:
Unknown entry

Source
  • staphylococcus aureus (strain usa300) (bacteria)
  • staphylococcus aureus (bacteria)
  • enterococcus faecalis (strain atcc 700802 / v583) (bacteria)
KeywordsTRANSCRIPTION / GTP SENSING / PLEIOTROPIC TRANSCRIPTION REGULATOR / DNA COMPLEX / GTP / LEUCINE BINDING / PLEIOTROPIC TRANSCRIPTION / REGULATOR

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