タイトル | Microbial beta-glucuronidases drive human periodontal disease etiology. |
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ジャーナル・号・ページ | Sci Adv, Vol. 9, Page eadg3390-eadg3390, Year 2023 |
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掲載日 | 2022年6月27日 (構造データの登録日) |
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著者 | Lietzan, A.D. / Simpson, J.B. / Walton, W.G. / Jariwala, P.B. / Xu, Y. / Boynton, M.H. / Liu, J. / Redinbo, M.R. |
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リンク | Sci Adv / PubMed:37146137 |
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手法 | X線回折 |
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解像度 | 1.6 - 2.3 Å |
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構造データ | PDB-8dhe: Tannerella forsythia beta-glucuronidase (mL1) 手法: X-RAY DIFFRACTION / 解像度: 2.2 Å PDB-8dhl: Tannerella forsythia beta-glucuronidase (L2) 手法: X-RAY DIFFRACTION / 解像度: 2.3 Å PDB-8dhv: Treponema lecithinolyticum beta-glucuronidase 手法: X-RAY DIFFRACTION / 解像度: 1.6 Å PDB-8dhw: Treponema lecithinolyticum beta-glucuronidase in complex with a UNC4917-glucuronide conjugate 手法: X-RAY DIFFRACTION / 解像度: 1.75 Å PDB-8e72: Treponema lecithinolyticum beta-glucuronidase in complex with a ciprofloxacin-glucuronide conjugate 手法: X-RAY DIFFRACTION / 解像度: 1.95 Å |
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化合物 | ChemComp-E0V: 4-(4-beta-D-glucopyranuronosylpiperazin-1-yl)-2,7-bis(methylamino)pyrido[3',2':4,5]thieno[3,2-d]pyrimidine
ChemComp-USL: 3-carboxy-1-cyclopropyl-6-fluoro-7-(4-beta-D-glucopyranuronosyl-3,4-dihydropyrazin-1(2H)-yl)-4-oxo-1,4-dihydroquinoline
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由来 | tannerella forsythia (バクテリア) treponema lecithinolyticum (バクテリア)
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キーワード | HYDROLASE / Glycoside hydrolase family 2 / TIM barrel domain |
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