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TitleCrystal structure of dihydrofolate reductase from the filarial nematode W. bancrofti in complex with NADPH and folate.
Journal, issue, pagesPlos Negl Trop Dis, Vol. 17, Page e0011303-e0011303, Year 2023
Publish dateAug 18, 2022 (structure data deposition date)
AuthorsLange, K. / Frey, K.M. / Eck, T. / Janson, C.A. / Gubler, U. / Goodey, N.M.
External linksPlos Negl Trop Dis / PubMed:37104530
MethodsX-ray diffraction
Resolution2.47 Å
Structure data

PDB-8e4f:
Crystal structure of dihydrofolate reductase (DHFR) from the filarial nematode W. bancrofti in complex with NADPH and folate
Method: X-RAY DIFFRACTION / Resolution: 2.47 Å

Chemicals

ChemComp-NAP:
NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE

ChemComp-FOL:
FOLIC ACID

ChemComp-NA:
Unknown entry

ChemComp-HOH:
WATER

Source
  • wuchereria bancrofti (agent of lymphatic filariasis)
KeywordsOXIDOREDUCTASE / Reductase

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