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TitleHuman and bacterial TatD enzymes exhibit apurinic/apyrimidinic (AP) endonuclease activity.
Journal, issue, pagesNucleic Acids Res., Vol. 51, Page 2838-2849, Year 2023
Publish dateSep 8, 2022 (structure data deposition date)
AuthorsDorival, J. / Eichman, B.F.
External linksNucleic Acids Res. / PubMed:36881763
MethodsX-ray diffraction
Resolution1.5 Å
Structure data

PDB-8efg:
Crystal structure of human TATDN1 bound to dAMP and two zinc ions
Method: X-RAY DIFFRACTION / Resolution: 1.5 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-NA:
Unknown entry

ChemComp-GOL:
GLYCEROL

ChemComp-D5M:
2'-DEOXYADENOSINE-5'-MONOPHOSPHATE

ChemComp-3D1:
(2R,3S,5R)-5-(6-amino-9H-purin-9-yl)-tetrahydro-2-(hydroxymethyl)furan-3-ol

ChemComp-ADE:
ADENINE

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHYDROLASE / Nuclease / TatD / AP-endonuclease / exonuclease

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