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Structure paper

TitleThe dynamic nature of netrin-1 and the structural basis for glycosaminoglycan fragment-induced filament formation.
Journal, issue, pagesNat Commun, Vol. 14, Page 1226-1226, Year 2023
Publish dateJan 14, 2021 (structure data deposition date)
AuthorsMeier, M. / Gupta, M. / Akgul, S. / McDougall, M. / Imhof, T. / Nikodemus, D. / Reuten, R. / Moya-Torres, A. / To, V. / Ferens, F. ...Meier, M. / Gupta, M. / Akgul, S. / McDougall, M. / Imhof, T. / Nikodemus, D. / Reuten, R. / Moya-Torres, A. / To, V. / Ferens, F. / Heide, F. / Padilla-Meier, G.P. / Kukura, P. / Huang, W. / Gerisch, B. / Morgelin, M. / Poole, K. / Antebi, A. / Koch, M. / Stetefeld, J.
External linksNat Commun / PubMed:36869049
MethodsX-ray diffraction
Resolution3.21 - 5.99 Å
Structure data

PDB-7ler:
Netrin-1 filament assembly
Method: X-RAY DIFFRACTION / Resolution: 5.99 Å

PDB-7lrf:
Netrin-1 in complex with SOS
Method: X-RAY DIFFRACTION / Resolution: 3.21 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-PEG:
DI(HYDROXYETHYL)ETHER

ChemComp-CA:
Unknown entry

ChemComp-NA:
Unknown entry

ChemComp-NHE:
2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID / pH buffer*YM

ChemComp-CL:
Unknown entry

ChemComp-HOH:
WATER

Source
  • gallus gallus (chicken)
KeywordsSIGNALING PROTEIN / heparin binding protein / filament / self assembly / localization / sulfate binding

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