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TitleGut microbial metabolism of 5-ASA diminishes its clinical efficacy in inflammatory bowel disease.
Journal, issue, pagesNat Med, Vol. 29, Page 700-709, Year 2023
Publish dateSep 2, 2022 (structure data deposition date)
AuthorsMehta, R.S. / Mayers, J.R. / Zhang, Y. / Bhosle, A. / Glasser, N.R. / Nguyen, L.H. / Ma, W. / Bae, S. / Branck, T. / Song, K. ...Mehta, R.S. / Mayers, J.R. / Zhang, Y. / Bhosle, A. / Glasser, N.R. / Nguyen, L.H. / Ma, W. / Bae, S. / Branck, T. / Song, K. / Sebastian, L. / Pacheco, J.A. / Seo, H.S. / Clish, C. / Dhe-Paganon, S. / Ananthakrishnan, A.N. / Franzosa, E.A. / Balskus, E.P. / Chan, A.T. / Huttenhower, C.
External linksNat Med / PubMed:36823301
MethodsX-ray diffraction
Resolution1.89 Å
Structure data

PDB-8ecm:
Crystal Structure Analysis of Acetyl-CoA acetyltransferase from Firmicutes bacterium
Method: X-RAY DIFFRACTION / Resolution: 1.89 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • firmicutes bacterium (bacteria)
KeywordsTRANSFERASE / Acetyl-CoA acetyltransferase

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