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TitleStructure of Helicobacter pylori dihydroneopterin aldolase suggests a fragment-based strategy for isozyme-specific inhibitor design.
Journal, issue, pagesCurr Res Struct Biol, Vol. 5, Page 100095-100095, Year 2023
Publish dateOct 20, 2022 (structure data deposition date)
AuthorsShaw, G.X. / Fan, L. / Cherry, S. / Shi, G. / Tropea, J.E. / Ji, X.
External linksCurr Res Struct Biol / PubMed:36820301
MethodsX-ray diffraction
Resolution1.49 Å
Structure data

PDB-8evk:
Crystal structure of Helicobacter pylori dihydroneopterin aldolase (DHNA)
Method: X-RAY DIFFRACTION / Resolution: 1.49 Å

Chemicals

ChemComp-PE0:
PTERINE

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-HOH:
WATER

Source
  • helicobacter pylori g27 (bacteria)
KeywordsLYASE / Inhibitor / Complex / Aldolase

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