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-Structure paper
Title | Monobody Inhibitor Selective to the Phosphatase Domain of SHP2 and its Use as a Probe for Quantifying SHP2 Allosteric Regulation. |
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Journal, issue, pages | J. Mol. Biol., Vol. 435, Page 168010-168010, Year 2023 |
Publish date | Feb 5, 2022 (structure data deposition date) |
Authors | Sha, F. / Kurosawa, K. / Glasser, E. / Ketavarapu, G. / Albazzaz, S. / Koide, A. / Koide, S. |
External links | J. Mol. Biol. / PubMed:36806475 |
Methods | X-ray diffraction |
Resolution | 2.39 Å |
Structure data | PDB-7tvj: |
Chemicals | ChemComp-FLC: ChemComp-HOH: |
Source |
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Keywords | SIGNALING PROTEIN/IMMUNE SYSTEM / Monobody / SHP2 / Phosphatase / Complex / Inhibitor / Signaling / SIGNALING PROTEIN-IMMUNE SYSTEM complex |