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Structure paper

TitleA RhoA structure with switch II flipped outward revealed the conformational dynamics of switch II region.
Journal, issue, pagesJ. Struct. Biol., Vol. 215, Page 107942-107942, Year 2023
Publish dateFeb 17, 2022 (structure data deposition date)
AuthorsJiang, H. / Zu, S. / Lu, Y. / Sun, Z. / Adeerjiang, A. / Guo, Q. / Zhang, H. / Dong, C. / Wu, Q. / Ding, H. ...Jiang, H. / Zu, S. / Lu, Y. / Sun, Z. / Adeerjiang, A. / Guo, Q. / Zhang, H. / Dong, C. / Wu, Q. / Ding, H. / Du, D. / Wang, M. / Liu, C. / Tang, Y. / Liang, Z. / Luo, C.
External linksJ. Struct. Biol. / PubMed:36781028
MethodsX-ray diffraction
Resolution1.50028778245 - 1.7994492129 Å
Structure data

PDB-7wza:
An open conformation Form 1 of switch II for RhoA
Method: X-RAY DIFFRACTION / Resolution: 1.50028778245 Å

PDB-7wzc:
An open conformation Form2 of switch II for RhoA GDP-bound state
Method: X-RAY DIFFRACTION / Resolution: 1.7994492129 Å

Chemicals

ChemComp-GDP:
GUANOSINE-5'-DIPHOSPHATE / GDP, energy-carrying molecule*YM

ChemComp-MG:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-GOL:
GLYCEROL

Source
  • homo sapiens (human)
KeywordsCELL INVASION / small GTPase / Rho family / Rho family member

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