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Structure paper

TitleStructural similarities between the metacyclic and bloodstream form variant surface glycoproteins of the African trypanosome.
Journal, issue, pagesPlos Negl Trop Dis, Vol. 17, Page e0011093-e0011093, Year 2023
Publish dateSep 16, 2022 (structure data deposition date)
AuthorsChandra, M. / Dakovic, S. / Foti, K. / Zeelen, J.P. / van Straaten, M. / Aresta-Branco, F. / Tihon, E. / Lubbehusen, N. / Ruppert, T. / Glover, L. ...Chandra, M. / Dakovic, S. / Foti, K. / Zeelen, J.P. / van Straaten, M. / Aresta-Branco, F. / Tihon, E. / Lubbehusen, N. / Ruppert, T. / Glover, L. / Papavasiliou, F.N. / Stebbins, C.E.
External linksPlos Negl Trop Dis / PubMed:36780870
MethodsX-ray diffraction
Resolution1.26 - 1.949 Å
Structure data

PDB-8b3b:
Structure of metacyclic VSG (mVSG) 531 from Trypanosoma brucei
Method: X-RAY DIFFRACTION / Resolution: 1.949 Å

PDB-8b3e:
Variant Surface Glycoprotein VSG397
Method: X-RAY DIFFRACTION / Resolution: 1.26 Å

PDB-8b3w:
Structure of metacyclic VSG (mVSG) 1954 from Trypanosoma brucei
Method: X-RAY DIFFRACTION / Resolution: 1.681 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-BMA:
beta-D-mannopyranose

ChemComp-MAN:
alpha-D-mannopyranose

ChemComp-HOH:
WATER

ChemComp-BR:
BROMIDE ION

Source
  • trypanosoma brucei (eukaryote)
  • trypanosoma brucei brucei (eukaryote)
KeywordsMEMBRANE PROTEIN / VSG / trypanosome / trypanosoma / metacyclic / Variant surface glycoprotein / Trypanosomiasis / Glycosylation

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