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TitlePol beta /XRCC1 heterodimerization dictates DNA damage recognition and basal Pol beta protein levels without interfering with mouse viability or fertility.
Journal, issue, pagesDNA Repair (Amst), Vol. 123, Page 103452-103452, Year 2023
Publish dateAug 9, 2022 (structure data deposition date)
AuthorsKoczor, C.A. / Thompson, M.K. / Sharma, N. / Prakash, A. / Sobol, R.W.
External linksDNA Repair (Amst) / PubMed:36702010
MethodsX-ray diffraction
Resolution1.65 - 1.8 Å
Structure data

PDB-8e10:
Structure of mouse polymerase beta
Method: X-RAY DIFFRACTION / Resolution: 1.65 Å

PDB-8e11:
Structure of mouse DNA polymerase Beta (PolB) mutant
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

Chemicals

ChemComp-MLA:
MALONIC ACID

ChemComp-HOH:
WATER

ChemComp-ACT:
ACETATE ION

Source
  • mus musculus (house mouse)
KeywordsTRANSFERASE / DNA polymerase / DNA binding / base excision repair

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