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Structure paper

TitleStructural Insights Uncover the Specific Phosphoinositide Recognition by the PH1 Domain of Arap3.
Journal, issue, pagesInt J Mol Sci, Vol. 24, Year 2023
Publish dateJul 18, 2022 (structure data deposition date)
AuthorsZhang, Y. / Ge, L. / Xu, L. / Liu, Y. / Wang, J. / Liu, C. / Zhao, H. / Xing, L. / Wu, B.
External linksInt J Mol Sci / PubMed:36674645
MethodsX-ray diffraction
Resolution2.099 - 3.3 Å
Structure data

PDB-7yir:
Crystal structure of N-terminal PH domain of ARAP3 protein from human
Method: X-RAY DIFFRACTION / Resolution: 2.099 Å

PDB-7yis:
Crystal structure of N-terminal PH domain of ARAP3 protein in complex with inositol 1,3,4,5-tetrakisphosphate
Method: X-RAY DIFFRACTION / Resolution: 3.3 Å

Chemicals

ChemComp-PEG:
DI(HYDROXYETHYL)ETHER

ChemComp-HOH:
WATER

ChemComp-4PT:
(2R)-3-{[(S)-{[(2S,3R,5S,6S)-2,6-DIHYDROXY-3,4,5-TRIS(PHOSPHONOOXY)CYCLOHEXYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-2-(1-HYDROXY

Source
  • homo sapiens (human)
KeywordsCYTOSOLIC PROTEIN / ARAP3 / PH domain / complex / inositol 1 / 3 / 4 / 5-tetrakisphosphate

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