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-Structure paper
| Title | Discovery of High-Affinity Small-Molecule Binders of the Epigenetic Reader YEATS4. |
|---|---|
| Journal, issue, pages | J. Med. Chem., Vol. 66, Page 460-472, Year 2023 |
| Publish date | Jul 5, 2022 (structure data deposition date) |
 Authors | Londregan, A.T. / Aitmakhanova, K. / Bennett, J. / Byrnes, L.J. / Canterbury, D.P. / Cheng, X. / Christott, T. / Clemens, J. / Coffey, S.B. / Dias, J.M. ...Londregan, A.T. / Aitmakhanova, K. / Bennett, J. / Byrnes, L.J. / Canterbury, D.P. / Cheng, X. / Christott, T. / Clemens, J. / Coffey, S.B. / Dias, J.M. / Dowling, M.S. / Farnie, G. / Fedorov, O. / Fennell, K.F. / Gamble, V. / Gileadi, C. / Giroud, C. / Harris, M.R. / Hollingshead, B.D. / Huber, K. / Korczynska, M. / Lapham, K. / Loria, P.M. / Narayanan, A. / Owen, D.R. / Raux, B. / Sahasrabudhe, P.V. / Ruggeri, R.B. / Saez, L.D. / Stock, I.A. / Thuma, B.A. / Tsai, A. / Varghese, A.E. |
 External links | J. Med. Chem. / PubMed:36562986 |
| Methods | X-ray diffraction |
| Resolution | 2.58 Å |
| Structure data |  PDB-8dkb: |
| Chemicals |  ChemComp-SJI:  ChemComp-HOH: |
| Source |
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 Keywords | PROTEIN BINDING / histone binding / lysine-acetylated histone binding |
homo sapiens (human)